Module Details for the Academic Year 2023/2024
NEUR40020 Synaptic plasticity | ||||
| Credits | 5 | Subject | Neuroscience | |
| Level | 4 | School | Biomolecular & Biomed Science | |
| Semester | Semester One | Coordinator | Professor John OConnor | |
| This module forms part of the core curriculum for the BSc. Neuroscience degree. It covers advanced topics in synaptic plasticity in the CNS, including the molecular mechanisms underlying long-term potentiation (LTP) and long-term depression (LTD) in the hippocampus. The role of endocannabinoid signalling in the hippocampus and plasticity at voltage gated sodium channels will also be covered. A strong emphasis will be placed on the mechanisms of signal transduction in LTP, including the role of AMPA and NMDA receptors. Students will be expected to read recent publications in the field of plasticity both for final exam. It is strongly recommended that students have taken BMOL30080 or other modules with similar learning outcomes. | ||||
On successful completion of the module students should be able to:
1. Critically evaluate recent research findings in synaptic plasticity including LTP and LTD.
2. Demonstrate a comprehensive understanding of the molecular mechanisms of LTP.
3. Demonstrate a comprehensive understanding of the mechanisms of endocannabinoid signaling in the hippocampus.
4. Discuss the application of modern research methods to studying problems in the field of synaptic plasticity.
1. Critically evaluate recent research findings in synaptic plasticity including LTP and LTD.
2. Demonstrate a comprehensive understanding of the molecular mechanisms of LTP.
3. Demonstrate a comprehensive understanding of the mechanisms of endocannabinoid signaling in the hippocampus.
4. Discuss the application of modern research methods to studying problems in the field of synaptic plasticity.
| Item | Workload |
|---|---|
| Autonomous Student Learning | 68 hours |
| Specified Learning Activities | 30 hours |
| Lectures | 12 hours |
| Description | FINAL | Timing |
|---|---|---|
| Examination :2 hour written examination | 100% of Final Grade | 2 Hour End Of Trimester Exam |
| Presentation :Presentation from a relevant journal | 0% of Final Grade | Varies Over The Trimester |
Resit Opportunities
End of Semester Exam
Remediation
If you fail this module you may repeat, resit or substitute where permissible
End of Semester Exam
Remediation
If you fail this module you may repeat, resit or substitute where permissible
Recommended - An understanding of membrane biology such as BMOL30080 or equivalent learning is recommended
Curricular information is subject to change