STAT40230 Survival Analysis

Academic Year 2013/2014

The basic concepts and methods in the analysis of survival data will be covered. We begin with the topics of censoring, life tables, the Kaplan-Meier estimator and the exponential, Weibull, Gamma and extreme value distributions. Nonparametric methods for comparing two or more samples- the logrank (Mantel Haenszel) and Wilcoxon tests as well as parametric methods - Wald's test and the likelihood ratio test will be explored. For regression data we examine the use of Cox's proportional hazards model and accelerated failure time models. Methods for choosing a model and modeling of time-dependent covariates are explored. The topics are illustrated using numerical examples throughout. The survival modules in the statistical software package SAS and R will be taught. Typewritten notes for the course will be provided. The lectures will be shared with final year undergraduates but there will be a different exam and more reading will be expected from Master's students.

Show/hide contentOpenClose All

Curricular information is subject to change

Learning Outcomes:

On successful completion of this module students should be able to explain the fundamental principles of survival analysis and why survival data requires special methods. They should be able to demonstrate knowledge and understanding of the concept of censored data and the methods developed to deal with it and with common distributions used in survival analysis. They should be able to produce Kaplan-Meier graphs, explain the use of the well known Cox model and accelerated failure time models. They will be able to demonstrate a critical understanding of how the methods they have learnt can be placed into the context of standard statistical theory. They will have developed skills in analysing sets of survival data and interpreting the results using SAS (and R). Postgraduate students are expected to demonstarte a deeper knowledge and understanding than undergraduates.

Student Effort Hours: 
Student Effort Type Hours
Lectures

24

Computer Aided Lab

10

Specified Learning Activities

36

Autonomous Student Learning

75

Total

145

 
Requirements, Exclusions and Recommendations
Learning Requirements:

Probability and distribution theory. Inference and hypothesis testing. Linear models, ANOVA and multiple regression.



Module Requisites and Incompatibles
Incompatibles:
Survival Analysis (STAT40040)

 
Description % of Final Grade Timing
Examination: 2 hour exam

80

2 hour End of Trimester Exam
Assignment: Approximately 8 assignments

20

Varies over the Trimester

Compensation

This module is not passable by compensation

Resit Opportunities

End of Semester Exam

Remediation

If you fail this module you may repeat, resit or substitute where permissible