GENE40040 Model organism genetics: a modern experimental approach

Academic Year 2020/2021

This module addresses advanced topics in how the genetics of eukaryotic model organisms are used to understand human cell biology and disease. Model organisms are genetically tractable experimental tools used to provide information about more complex systems, including humans, which are more difficult to study directly. Topics covered will include genomic, proteomic and drug discovery analysis using unicellular yeast, primary cilia function in plants (Chlamydomonas reinhardtii), worms (Caenorhabditis elegans) and mice, and animal models of human disease. Innovative model organism-based experimental technologies will be discussed, such as forward and reverse genetics screening and genome-wide protein interaction techniques. It is recommended that students have taken BMOL30050 (bioinformatics, genomics and proteomics) or other modules with similar learning outcomes.

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Curricular information is subject to change

Learning Outcomes:

On completion of this module students should be able to:1. Demonstrate an understanding of how model organisms are used in modern biomedical research 2.Evaluate the use of model organisms in research
3. Critically assess the use of large-scale screening methods.

Indicative Module Content:

Student Effort Hours: 
Student Effort Type Hours
Lectures

12
Autonomous Student Learning

100
Total

112
Approaches to Teaching and Learning:
lectures; critical writing; case-based learning 
Requirements, Exclusions and Recommendations
Learning Recommendations:

It is strongly recommended that students have taken BMOL30050 (Bioinformatics, genomics and proteomics) or other modules with similar learning outcomes.


Module Requisites and Incompatibles
Not applicable to this module.
 
Assessment Strategy  
Description Timing Open Book Exam Component Scale Must Pass Component % of Final Grade
Assignment: paper review and 1 hr written exam Throughout the Trimester n/a Graded No

20
Examination: End semester exam 2 hour End of Trimester Exam No Graded No

80

Carry forward of passed components
Yes
 
Resit In Terminal Exam
Summer Yes - 2 Hour
Please see Student Jargon Buster for more information about remediation types and timing. 
Feedback Strategy/Strategies

• Feedback individually to students, post-assessment
• Online automated feedback

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