GENE30070 Undergraduate Research 2

Academic Year 2023/2024

This is a computational research-based module, aimed at students with a strong interest in genomics, genetics, microbiology, computational biology and/or bioinformatics. The module follows on from GENE30060, but it is not necessary to take both. In GENE30070 students will analyse whole genome sequence data, derived from next generation sequencing of yeasts collected from Irish soil, or obtained from other sources. Most of this data will never have been assembled or analysed previously. Students will use computational methods to assemble and annotate genomes and to propose and address research hypotheses. The approaches used and questions posed will be determined by student input. The module will provide training in state-of-the art technologies in genome analysis. In previous years, some of the analyses have been accepted for publication in scientific journals. The module therefore provided an opportunity to engage in novel research. No previous coding experience is required, but the module may be taken together with a programming module (for example, GENE30040). Students will need their own laptop/computer (not tablet) for the duration of the module. The module assessment will include an in-trimester computer-based exam (50%), assessment of lab book and genome assembly and analysis (30%), and written presentation of results (20%).