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Curricular information is subject to change
On completion of this module students should be able to:1. Define and illustrate major concepts in genomics and proteomics 2. Identify and compare relevant technologies in genome and proteome research 3. Using examples, describe the application of high-throughput genomics and proteomics technology to address problems and questions in biological sciences and medicine 4. Demonstrate competency in the basic application of a prominent proteomics technique, i.e. the identification and comparison of proteins from complex samples by 2D gelelectrophoresis, including bioinformatics methods to analyse mass spectrometry data.
Indicative Module Content:1. Introduction to genomics (SG)
2. Next Generation sequencing (SG)
3. Bacterial genomics (SG)
4. Comparative bacterial genomics (SG)
5. Sequencing eukaryotic genomes (GB)
6. The human genome (GB)
7. Bioarchaelogy and the movement of human populations (GB)
8. Transcriptomics: microarrays (GB)
9. Transcriptomics: novel approaches (GB)
10. Protein function analysis – knockouts (JH)
11. Protein function analysis – RNA interference (JH)
12. Protein chips: generation and uses (JH)
13. 2D gel electrophoresis (JH)
14. Mass spectrometry (JH)
15. Mass spectrometry – Applications & Quantitative Methods (JH)
16. Analysis of protein-protein interactions - Yeast two hybrid analysis (JH)
17. Analysis of protein complexes - Affinity purification (JH)
Student Effort Type | Hours |
---|---|
Lectures | 20 |
Practical | 25 |
Autonomous Student Learning | 60 |
Total | 105 |
It is recommended that students taking this module will have successfully completed BIOC20010 and either BMOL20010 or GENE20010, or other modules with equivalent learning outcomes.
Description | Timing | Component Scale | % of Final Grade | ||
---|---|---|---|---|---|
Continuous Assessment: Practical, lab report and practical exam | Varies over the Trimester | n/a | Graded | No | 30 |
Examination: 2hr written examination | 2 hour End of Trimester Exam | No | Graded | No | 70 |
Resit In | Terminal Exam |
---|---|
Autumn | No |
• Feedback individually to students, post-assessment
• Group/class feedback, post-assessment
Feedback will be given to individual students on the lab report through VLE. Feedback will be given to students through VLE following grading of the exam outlining expected answers (bullet point model answers) and criteria for different grade categories (e.g. rubrics). If requested, individual feedback will be given to students post-assessment.
Name | Role |
---|---|
Professor Geraldine Butler | Lecturer / Co-Lecturer |
Professor Stephen Gordon | Lecturer / Co-Lecturer |
Ms Aimee Jones | Tutor |