BMOL30030 Regulation of Gene Expression

Academic Year 2019/2020

This module will be an advanced course on the transmission of genetic information. The primary focus will be to obtain a detailed understanding of the general and more specific mechanisms involved in the control of gene expression in both prokaryotic and in eukaryotic systems. The course will begin with the general mechanism of transcription, RNA polymerases and the various classes of transcription factors. Thereafter, specific aspects pertaining to general and specialised mechanisms of gene expression and transcriptional regulation in various prokaryotic and eukaryotic systems will be examined.This module is highly recommended for students intending to take GENE40030 in Stage 4.

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Curricular information is subject to change

Learning Outcomes:

On completion of this module students should be able to:· Explain the fundamental mechanisms of transcription in prokaryotes and eukaryotes,· Explain the main factors regulating gene expression in those systems,· Through specific examples, describe various transcriptional regulatory mechanisms in either prokaryotes or eukaryotes,· Through specific examples and/or through laboratory-based practicals, describe the experimental approaches to investigate the control of gene expression in prokaryotes and/or eukaryotes.

Student Effort Hours: 
Student Effort Type Hours




Specified Learning Activities


Autonomous Student Learning




Approaches to Teaching and Learning:
The module is comprised of 20 lectures and 4 x 3 hour lab based practicals (3 wet lab and one dry lab based practical).

During wet based practical labs, students will work in pairs and experimental work will be guided by an experienced teaching tutor.

Requirements, Exclusions and Recommendations
Learning Recommendations:

It is recommended that students taking this module will have successfully completed either BMOL20010 or GENE20010, or other modules with equivalent learning outcomes.

Module Requisites and Incompatibles
Not applicable to this module.  
Assessment Strategy  
Description Timing Open Book Exam Component Scale Must Pass Component % of Final Grade
Continuous Assessment: practical reports and assessment of practical material Varies over the Trimester n/a Graded No


Examination: Written exam on the lecture course duration 2 hr 2 hour End of Trimester Exam No Graded No


Carry forward of passed components
Resit In Terminal Exam
Spring Yes - 2 Hour
Please see Student Jargon Buster for more information about remediation types and timing. 
Feedback Strategy/Strategies

• Feedback individually to students, post-assessment
• Online automated feedback

How will my Feedback be Delivered?

Students submit practical report within 1 week of undertaking the practical. Report grade and feedback is provided through Brightspace.

Name Role
Ms Gillian Carney Tutor
Ms Rebecca Gorry Tutor
Sarah Mc Cormack Tutor
Mr Conor Quinn Tutor
Ms Rebecca Sheridan Tutor
Mr Yunjie Wu Tutor
Timetabling information is displayed only for guidance purposes, relates to the current Academic Year only and is subject to change.  
Lecture Offering 1 Week(s) - 1, 2, 3, 4, 5, 6, 7, 9, 10, 11, 12 Mon 14:00 - 14:50
Lecture Offering 1 Week(s) - Autumn: All Weeks Wed 16:00 - 16:50
Laboratory Offering 1 Week(s) - 3, 5, 7, 11 Tues 10:00 - 12:50
Laboratory Offering 1 Week(s) - 9 Tues 10:00 - 12:50
Laboratory Offering 2 Week(s) - 3, 5, 7, 11 Fri 10:00 - 12:50
Laboratory Offering 2 Week(s) - 9 Fri 10:00 - 12:50