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Curricular information is subject to change
On completion of this module, students should be able to:
1. Develop a deeper understanding and appreciation of the role of proteins and enzymes in a variety of biochemical processes; 2. Characterise the function of various proteins in physiological processes and disease; 3. Develop competencies in self-directed group learning and presentation skills
Lecture list:
1 Module Intro
2 Transport across membranes - introduction
3 ABC transporters
4 SLC transporters, nutrient transport
5 Transporters in the brain
6 Transporter research - a biochemist's approach
7 Protein structure – CFTR and Haemoglobin
8 Protein mis-folding and accumulation: Alzheimer’s disease, prion diseases
9 Heat shock proteins and their role in diseases: (immunodominant antigen in infection; role in autoimmune disease)
10 Subject presentation - Biochemistry
11 Serine proteases and Blood clotting
12 Proteomics and protein research
13 The Cell Cycle: regulation by protein kinases and phosphatases
14 Cell Cycle checkpoints in regulation of cell division
15 DNA Damage & Repair pathways in health and disease
16 Circadian Clock and Cell Cycle: interconnected biological circuits
17 Stem cells and Stem cell differentiation
18 Antibodies – Immunotherapies. Antibodies as research tools
19 Diagnostic proteins and peptides in human disease
20 Fluorescent proteins and applications
21 Peptides as biotherapeutics
22 Recombinant proteins and peptides. Bioprocessing
Student Effort Type | Hours |
---|---|
Lectures | 24 |
Small Group | 10 |
Specified Learning Activities | 20 |
Autonomous Student Learning | 50 |
Total | 104 |
Not applicable to this module.
Description | Timing | Component Scale | % of Final Grade | ||
---|---|---|---|---|---|
Group Project: Group project | Throughout the Trimester | n/a | Graded | No | 25 |
Examination: End-of-Semester exam | 2 hour End of Trimester Exam | No | Graded | No | 75 |
Resit In | Terminal Exam |
---|---|
Autumn | Yes - 2 Hour |
• Feedback individually to students, on an activity or draft prior to summative assessment
• Feedback individually to students, post-assessment
• Group/class feedback, post-assessment
• Online automated feedback
• Peer review activities
Feedback will be given to individual and groups of students on the group project through VLE. The class will be asked to provide feedback (peer review activity) on group project presentations. Test exam questions will be provided through VLE with automated feedback prior to end-of-semester exam. If requested, individual feedback will be given to students post-assessment.
Name | Role |
---|---|
Assoc Professor Siobhán McClean | Lecturer / Co-Lecturer |
Assoc Professor Margaret McGee | Lecturer / Co-Lecturer |
Dr Jens Rauch | Lecturer / Co-Lecturer |